An unholy alliance—Colon cancer cells in situ co-opt fibroblasts in...
It means cancer "in place" but a carcinoma "in situ" often does not want to keep its place. Standing between a cancer cell in situ and the surrounding tissue of fibroblasts and extracellular matrix is...
View ArticleEnzyme linked to respiratory system development in fruit flies comes from...
Research from the RIKEN Center for Developmental Biology has revealed that development of the respiratory system in fruit flies is controlled by a regulatory enzyme that is manufactured in the fat...
View ArticleHow to myelinate a nerve
(Medical Xpress)—Demyelinating diseases, like MS or ALS, attack an otherwise healthy nervous system and leave its owner a prisoner in their own body. The harder big pharma searches for—and fails to...
View ArticleResearchers find promising new biomarkers for concussion
By looking at the molecular aftermath of concussion in an unusual way, a team of researchers at Brown University and the Lifespan health system has developed a candidate panel of blood biomarkers that...
View ArticleHarnessing the clinical potential of microvesicles released from cancer cells
Over the past few years, extracellular vesicles, or membrane sacs secreted from cells, have emerged as important mediators by which cells communicate with their surroundings to regulate a diverse range...
View ArticleNew mechanism triggers endothelial permeability in vivo
A single layer of endothelial cells and extracellular matrix lines the inside of blood vessels, like the inner tube inside a bicycle tire. Injury and inflammation can damage this thin layer, allowing a...
View ArticlePulsed electrical fields may provide improved skin rejuvenation
A new approach to skin rejuvenation developed at Massachusetts General Hospital (MGH) may be less likely to have unintended side effects such as scarring and altered pigmentation. In the online journal...
View ArticleResearchers illuminate key role of NOX proteins in liver disease
Researchers at the University of California, San Diego School of Medicine have demonstrated a direct connection between two signaling proteins and liver fibrosis, a scarring process underlying chronic...
View ArticleDevelopment of brain-friendly interfaces
Recent research published in the journal Microsystems & Nanoengineering could eventually change the way people living with prosthetics and spinal cord injury lead their lives.
View ArticleMice research boosts muscle repair capabilities
Research using mice and rat quadricep muscles to better understand muscle repair processes has utilised an artificial medium to study how natural muscle scaffolds repair themselves.
View ArticleCancer cell collaborators smooth the way for cancer cells to metastasize
At ASCB 2015, Vanderbilt researchers show how metastasizing tumors use non-cancerous fibroblasts to make a migration highway through surrounding extracellular matrix.
View ArticleStudy finds how diabetes drug metformin inhibits progression of pancreatic...
Massachusetts General Hospital (MGH) investigators may have uncovered a novel mechanism behind the ability of the diabetes drug metformin to inhibit the progression of pancreatic cancer. In their...
View ArticleRosacea linked to increased risk of glioma
(HealthDay)—Rosacea is associated with a significantly increased risk of developing glioma, according to research published online Jan. 27 in JAMA Dermatology.
View ArticleBioprinting technique creates thick 3-D tissues composed of human stem cells...
A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University and the Harvard John A. Paulson School for Engineering and Applied Sciences (SEAS) has invented a method for 3D...
View ArticleROBO1 helps cells put up stiff resistance
A protein called ROBO1 may delay the progression of breast cancer, according to a paper published in The Journal of Cell Biology. The study, "Loss of miR-203 regulates cell shape and matrix adhesion...
View ArticleDecrypting a collagen's role in schizophrenia
A small peptide generated from a collagen protein may protect the brain from schizophrenia by promoting the formation of neuronal synapses, according to a paper published in The Journal of Cell...
View ArticleCancer cells remodel their environment to make it easier to reach nearby...
A new study from MIT reveals how cancer cells take some of their first steps away from their original tumor sites. This spread, known as metastasis, is responsible for 90 percent of cancer deaths.
View ArticleWaist-to-height ratio should be used as a screening tool for early health risks
Waist-to-height ratio is a simpler and more predictive indicator of the 'early heath risks' associated with central obesity than the complex 'matrix', based on BMI and waist circumference (WC),...
View ArticleAmerican doctors make new esophagus using stents and skin
American doctors have made a new esophagus for a young man, using donated skin tissue and metal stents, in the latest example of scientists creating body parts in the lab to help patients with few...
View ArticleAnti-fibrotic peptide shows early promise against interstitial lung disease
The results of preclinical studies by investigators at the Medical University of South Carolina (MUSC) reported in the April 2016 issue of Translational Research suggest that the M10 peptide could help...
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